Minecraft is a creative sandbox arena game currently being developed by Mojang. Though I cannot always have the time to do everyone's idea, I do like to invite the community to suggest ideas for more Machinimas! Typically, if I choose your idea, I will mention you in the video or description, and provide a link to your channel! I do that.well, because it's fun! I love engaging with the community like that! Learn how you can measure binding affinity and why it matters in science.What does aqua affinity do in Minecraft? Watch and learn!įilming and creating quality videos and Machinimas that can be fun for everyone to enjoy!
Without it, science, society, and life itself, would unquestionably be very different. It determines which people, things and biomolecules that go well together. In early-stage discovery, it’s used as the key selection parameter during candidate molecule screening and it’s further optimized during the hit-to-lead phase.Īffinity plays a crucial role in various aspects of our lives. It’s thanks to these tools that researchers are able to understand biological processes at the cellular level, they can characterize purified proteins and confirm structure-activity relations, study enzyme inhibition and understand the interactions between antibodies and their targets.Īffinity is also important in drug development. Over the last 50 years, scientists have creatively developed several technologies, like MST, that can measure the binding affinity between two molecules, which have become invaluable tools in science.
This biophysical parameter is so important that it represents the foundation of molecular recognition and communication.
The smaller its value, the greater the affinity between two molecules and vice-versa. Binding affinity is reported by the famous K d or equilibrium dissociation constant. It refers to the strength by which two (or more) molecules interact or bind. In the context of biology and biophysics, the meaning of “affinity” is not very different. Even people can have their perfect matches - or better said - have a strong affinity with others. While there are different definitions for the word “affinity”, its meaning in our daily lives is intuitively understood: a quality that makes things or people go well together.įollowing this definition, examples of affinity can easily be found: bread and butter, shoes and socks, or coffee and a sunrise. To others, it could just be that two things or people are a “good fit” for each other. Some people refer to it as a natural attraction.
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